Why Your Donation Matters Right Now

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We are closer than ever to the first potential treatment for DESSH.

 

For the first time, researchers have identified a promising repurposed drug candidate for DeSanto–Shinawi Syndrome — and The DESSH Foundation is playing a key role in advancing this possibility. Clinical trials are built on many coordinated efforts — and together, we are supporting essential areas such as:

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• Growing stem cell lines to understand how the drug works at the cellular level

• Advancing animal model research to establish safety and targeted effects

• Expanding the DESSH patient registry to meet FDA requirements

• Completing natural history studies that define measurable trial outcomes

• Building research partnerships and the infrastructure needed for trial design

• Preparing families and clinicians through education, translation, and clinical guidance​

 

Every single piece is critical. And every step requires funding.

 

Your donation directly accelerates our path to clinical trials.

You’re not only supporting families today — you’re helping build the scientific foundation that could finally bring treatment within reach.

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Help us turn possibility into reality.

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